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Merck
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A8509

Sigma-Aldrich

Lithium acetoacetate

≥90% (HPLC)

Sinónimos:

Acetoacetic acid lithium salt

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About This Item

Fórmula lineal:
CH3COCH2COOLi
Número de CAS:
3483-11-2
Peso molecular:
108.02
Beilstein/REAXYS Number:
5774841
MDL number:
MFCD00013060
UNSPSC Code:
12352100
PubChem Substance ID:
57653889
NACRES:
NA.22

assay

≥90% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

[Li+].CC(=O)CC([O-])=O

InChI

1S/C4H6O3.Li/c1-3(5)2-4(6)7;/h2H2,1H3,(H,6,7);/q;+1/p-1

InChI key

UTLRZTUJSMCBHB-UHFFFAOYSA-M

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Application

Lithium acetoacetate can be used as an acetoacetate standard for the measurement of acetoacetate in biological samples. It can also be used for the preparation of sodium acetoacetate.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análisis (COA)

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Isopropyl alcohol (IPA) is widely used as an industrial solvent and cleaning fluid. After ingestion or absorption, IPA is converted into acetone by alcohol dehydrogenase. However, in ketosis, acetone can be reduced to IPA. The aim of this study was
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BDH2 is a short-chain dehydrogenase/reductase family member involved in several biological and pathological processes, including the utilization of cytosolic ketone bodies, immunocyte regulation and tumor progression. In this study, we first revealed that BDH2 was downregulated in HCC tissues by
Seppo Parkkila et al.
Chemical communications (Cambridge, England), 48(29), 3551-3553 (2012-03-03)
Acetoacetic acid and R-3-hydroxy-butyric acid (BHB) are "ketone bodies", metabolites produced during the ketogenic diet. We discovered that they inhibit in the submicromolar-micromolar range several carbonic anhydrase (CA, EC 4.2.1.1) isoforms involved in relevant physiologic processes such as lipogenesis and
Mathieu Coincon et al.
The Journal of biological chemistry, 287(43), 36208-36221 (2012-08-22)
Crystal structures of divalent metal-dependent pyruvate aldolase, HpaI, in complex with substrate and cleavage products were determined to 1.8-2.0 Å resolution. The enzyme·substrate complex with 4-hydroxy-2-ketoheptane-1,7-dioate indicates that water molecule W2 bound to the divalent metal ion initiates C3-C4 bond
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