- A novel straightforward synthesis of 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF.
A novel straightforward synthesis of 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF.
Organic letters (2014-06-17)
Xiaowen Xu, Min Zhang, Huanfeng Jiang, Jia Zheng, Yiqun Li
PMID24933098
ABSTRACT
A novel straightforward synthesis of both symmetrical and unsymmetrical 2,4-disubstituted-1,3,5-triazines via aerobic copper-catalyzed cyclization of amidines with DMF as a one-carbon synthon has been developed. The presented method allows synthesizing the products that are currently inaccessible or challenging to prepare with the advantages of operational simplicity, broad substrate scope, and no need for prefunctionalized reagents, making it a highly practical approach to access various 2,4-disubstituted-1,3,5-triazines.
MATERIALS
Product Number
Brand
Product Description
Copper - O.F.H.C., foil, 0.5m coil, thickness 0.05mm, hard, 99.95+%
Copper - O.F.H.C., foil, 0.5m coil, thickness 0.1mm, coil width 100mm, hard, 99.95+%
Copper - O.F.H.C., foil, 100x100mm, thickness 0.25mm, annealed, 99.95+%
Copper - O.F.H.C., foil, 50x50mm, thickness 0.20mm, hard, 99.95+%
Copper - O.F.H.C., foil, 100x100mm, thickness 0.5mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 0.5m coil, thickness 0.006mm, hard, 99.95+%
Copper - O.F.H.C., foil, 150x150mm, thickness 0.25mm, annealed, 99.95+%
Copper - O.F.H.C., foil, 100x100mm, thickness 0.7mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 50x50mm, thickness 2.0mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 300x300mm, thickness 0.20mm, hard, 99.95+%
Copper - O.F.H.C., foil, 0.5m coil, thickness 0.05mm, annealed, 99.95+%
Copper - O.F.H.C., foil, 10m coil, thickness 0.05mm, coil width 10mm, annealed, 99.95+%
Copper - O.F.H.C., foil, 300x300mm, thickness 1.6mm, hard, 99.95+%
Copper - O.F.H.C., foil, 100x100mm, thickness 0.125mm, hard, 99.95+%
Copper, insulated wire, 100m, conductor diameter 0.1mm, insulation thickness 0.005mm, polyurethane insulation, 99.9%
Copper - O.F.H.C., wire reel, 5m, diameter 0.5mm, as drawn, 99.95+%
Copper - O.F.H.C., foil, 300x1000mm, thickness 2.0mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 100x100mm, thickness 1.0mm, half hard, 99.95+%
Copper - O.F.H.C., wire reel, 5m, diameter 0.125mm, annealed, 99.95+%
Copper - O.F.H.C., foil, 100x100mm, thickness 2.0mm, half hard, 99.95+%
Copper, insulated wire, 2m, conductor diameter 1.0mm, insulation thickness 0.25mm, PTFE (polytetrafluoroethylene) insulation
Copper - O.F.H.C., foil, 10m coil, thickness 0.010mm, coil width 25mm, hard, 99.95+%
Copper, insulated wire, 100m, conductor diameter 0.24mm, insulation thickness 0.25mm, PTFE (polytetrafluoroethylene) insulation
Copper - O.F.H.C., wire reel, 5m, diameter 0.25mm, as drawn, 99.95+%
Copper, insulated wire, 50m, conductor diameter 0.5mm, insulation thickness 0.06mm, polyimide insulation
Copper, insulated wire, 200m, conductor diameter 0.5mm, insulation thickness 0.06mm, polyimide insulation
Copper, insulated wire, 10m, conductor diameter 0.125mm, insulation thickness 0.01mm, polyimide insulation, 99.99%
Copper - O.F.H.C., foil, 150x150mm, thickness 0.125mm, hard, 99.95+%
Copper - O.F.H.C., foil, 300x300mm, thickness 0.1mm, half hard, 99.95+%
Copper - O.F.H.C., foil, 0.5m coil, thickness 0.05mm, coil width 300mm, half hard, 99.95+%