Voltage Gated
The majority of ion channels fall into two broad categories: voltage-gated ion channels (VGIC) and ligand-gated ion channels (LGIC). Members of the VGIC superfamily are usually closed at the resting potential of the cell. A change in the membrane potential causes conformational changes that result in the opening of the pore (voltage-dependent activation), which may be followed by a transitional conformational change (inactivation) to an inactivated state.1 The VGIC superfamily includes calcium channels, chloride channels, potassium channels and sodium channels. Other, smaller categories exist, such as the vanilloid (TRP) receptors, the ATP-gated channels, the cyclic nucleotide-gated channels (CNG) and aquaporins (water channels).
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Aquaporin (Water)
Antibodies to Water Channels
Calcium
Antibodies to Calcium Channels
Calcium Channel Modulators
Chloride
Antibodies to Chloride Channels
Chloride Channel Modulators
Potassium
Antibodies to Potassium Channels
Potassium Channel Modulators
Sodium
Antibodies to Sodium Channels
Sodium Channel Modulators
Other Ion Channels
Antibodies to Other Ion Channels
Ion Exchangers and Co-Transporters
Ion Probes
Ionophores
Antibodies to Ion Pumps
Ion Pump Inhibitors
Ion Channel Solutions page
References
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