Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells.

Fusaric Acid immunotoxicity and MAPK activation in normal peripheral blood mononuclear cells and Thp-1 cells.

Scientific reports (2017-06-10)

Shanel Dhani, Savania Nagiah, Dhaneshree B Naidoo, Anil A Chuturgoon

ABSTRACT

Fusaric acid (FA), a food-borne mycotoxin, is a potent divalent metal chelator. The human immune system is complex and susceptible to environmental insult however, the immunotoxity of FA remains unknown. We investigated the immunotoxicity of FA on human peripheral blood mononuclear cells (PBMCs) and Thp-1 cells. FA was cytotoxic to PBMCs (IC

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

A3854

Sigma-Aldrich

Anti-β-actina monoclonale, clone AC-15, purified from hybridoma cell culture

M8177

Sigma-Aldrich

Anti-p38 MAP Kinase, Activated (Diphosphorylated p38) antibody, Mouse monoclonal, clone P38-TY, purified from hybridoma cell culture, buffered aqueous solution