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[Proteolytic control of expression of Vibrio fischeri lux-operon genes in Escherichia coli cells].

Genetika (2010-09-29)
O E Mel'kina, I V Manukhov, G B Zavil'gel'skiĭ
ABSTRACT

The key elements of the regulatory system activating expression of the lux-operon genes in the sea bacteria Vibrio fischeri are the LuxR protein (an activator oftranscription) and N-(3-oxohexanoyl) L-homoserine lactone (an autoinducer, AI). It is shown that the ATP-dependent proteases ClpXP and Lon take part in the negative control of expression of the lux-operon genes and that AI protects the LuxR protein from proteolysis.

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Supelco
N-(β-Ketocaproyl)-DL-homoserine lactone, analytical standard