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  • Inhibition of esterase activity and an undercounting of circulating monocytes in a population of production workers.

Inhibition of esterase activity and an undercounting of circulating monocytes in a population of production workers.

Journal of occupational medicine. : official publication of the Industrial Medical Association (1986-03-01)
M S Levine, N L Fox, B Thompson, W Taylor, A C Darlington, J Van der Hoeden, E A Emmett, W Rutten
ABSTRACT

A cross-sectional review of routine employee health status examinations has identified an undercounting of circulating monocytes associated with an inhibition of a surface monocyte esterase, alpha-naphthyl butyrate esterase. It is postulated that this inhibition is associated with an organophosphate used in the production process. Correlation with routine measures of health status are presented.

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Sigma-Aldrich
1-Naphthyl butyrate, esterase substrate