Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.

Improved synthesis of a DNA-dependent protein kinase inhibitor IC86621.

Archives of pharmacal research (2012-05-04)

Girish Chandra, Varughese Alexander, Hyuk Woo Lee, Lak Shin Jeong

ABSTRACT

An improved synthesis of DNA-dependent protein kinase inhibitor, IC86621 is described. This developed method provides an easy access to this simple molecule by using amination, acetylation and Fries rearrangement reactions.

MATERIALI

N° Catalogo

Marchio

Descrizione del prodotto

101079

Sigma-Aldrich

3-Bromophenol, 98%