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  • Fluoroanalogs of DDT: superacidic BF3-H2O catalyzed facile synthesis of 1,1,1-trifluoro-2,2-diarylethanes and 1,1-difluoro-2,2-diarylethanes.

Fluoroanalogs of DDT: superacidic BF3-H2O catalyzed facile synthesis of 1,1,1-trifluoro-2,2-diarylethanes and 1,1-difluoro-2,2-diarylethanes.

Organic letters (2011-07-14)
G K Surya Prakash, Farzaneh Paknia, Thomas Mathew, Gzregorz Mlostoń, Jens P Joschek, George A Olah
ABSTRACT

The one-pot synthesis of 1,1,1-trifluoro- and 1,1-difluoro-2,2-diarylethanes from arenes and fluorinated hemiacetals in the BF(3)-H(2)O system is described. The reaction is simple, clean, and convenient, eliminating the use of organic solvents and other expensive acid systems. BF(3)-H(2)O is economic, is easy to prepare, and offers ample acidity required for this reaction.

MATERIALI
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Supelco
Boron trifluoride - 1-butanol solution, ~10% in 1-butanol (∼1.3 M), for GC derivatization, LiChropur