- Ionic liquid-assisted transdermal delivery of sparingly soluble drugs.
Ionic liquid-assisted transdermal delivery of sparingly soluble drugs.
Chemical communications (Cambridge, England) (2010-02-18)
Muhammad Moniruzzaman, Yoshiro Tahara, Miki Tamura, Noriho Kamiya, Masahiro Goto
PMID20162145
ABSTRACT
We report the first successful application of a novel IL-assisted non-aqueous microemulsion stabilized by a blend of two nontoxic surfactants, polyoxyethylene sorbitan monooleate (Tween-80), and sorbitan laurate (Span-20) for transdermal delivery of acyclovir, which is insoluble or sparingly soluble in water and most common organic liquids.
MATERIALI