SAB4200590

Anti-WHAMM (C-terminal) Produced in rabbit

affinity isolated antibody

• Codice UNSPSC: 12352203
• NACRES: NA.41
• Reattività contro le specie: human
• tecniche: immunoblotting: 1-2 μg/mL using whole extracts of HEK-293T cells overexpressing human WHAMM.
• citations: 2

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 200
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Stato: buffered aqueous solution
• PM: ~100 kDa
• Reattività contro le specie: human
• Concentrazione: ~1 mg/mL
• tecniche: immunoblotting: 1-2 μg/mL using whole extracts of HEK-293T cells overexpressing human WHAMM.
• N° accesso UniProt: Q8TF30
• Condizioni di spedizione: dry ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... WHAMM(123720)

Descrizione

Descrizione generale

WASP homologue associated with actin, membranes, and microtubules (WHAMM) is a nucleation promoting factor. It is located in the cis-Golgi and tubulo-vesicular membrane transport intermediates. WHAMM contains an N-terminal region, a coiled-coil region and a WCA region. It is located on the human chromosome at 15q25.2.

Specificità

Anti- WHAMM (C-terminal) recognizes human WHAMM.

Immunogeno

peptide corresponding to the C-terminal region of human WHAMM , conjugated to KLH.

Applicazioni

Anti-WHAMM (C-terminal) produced in rabbit may be used in immunoblotting.

Azioni biochim/fisiol

WASP homologue associated with actin, membranes, and microtubules (WHAMM) takes part in actin-related protein 2 & 3 (Arp2/3)-mediated actin polymerization, mediates Golgi membrane association and microtubule dynamics. It also takes part in the maintenance of Golgi structure and participates in vesicle transport between the endoplasmic reticulum and the Golgi apparatus.

Stato fisico

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

Stoccaggio e stabilità

For continuous use, store at 2–8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable