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P3761

Sigma-Aldrich

Pentobarbital sodium salt

Sinonimo/i:

5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal

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About This Item

Formula empirica (notazione di Hill):
C11H17N2NaO3
Numero CAS:
57-33-0
Peso molecolare:
248.25
Numero CE:
200-323-9
Numero MDL:
MFCD00070198
Codice UNSPSC:
41116107
ID PubChem:
24898448

Forma fisica

powder

Controllo stupefacenti

USDEA Schedule II; Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Solubilità

H2O: soluble
alcohol: soluble

Stringa SMILE

[Na].CCCC(C)C1(CC)C(=O)NC(=O)NC1=O

InChI

1S/C11H18N2O3.Na.H/c1-4-6-7(3)11(5-2)8(14)12-10(16)13-9(11)15;;/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16);;
PGOYUXGHADTNIB-UHFFFAOYSA-N

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Applicazioni

Pentobarbital sodium salt has been used as an anesthetic in rats and mice prior to various in vitro studies.

Azioni biochim/fisiol

Pentobarbital (PB) is a barbiturate and a ligand of the γ-aminobutyric acid subtype A (GABAA) receptor. It is a sedative anesthetic majorly used in rodent euthanasia. Pentobarbital possesses hypnotic functionality and muscle relaxing properties. It enhances GABAergic activity. Intraperitoneal injection of PB may result in loss of righting reflex (LORR) and heartbeat cessation.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H301,H336,H361d

Classi di pericolo

Acute Tox. 3 Oral - Repr. 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificati d'analisi (COA)

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