I5270

Anti-Interleukin-11 antibody produced in goat

IgG fraction of antiserum, lyophilized powder

• Sinonimo/i: Anti-IL-11
• Numero MDL: MFCD00212981
• Codice UNSPSC: 51111800
• NACRES: NA.41

Proprietà

• Origine biologica: goat
• Livello qualitativo: 100
• Coniugato: unconjugated
• Forma dell’anticorpo: IgG fraction of antiserum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: lyophilized powder
• Reattività contro le specie: human
• tecniche: neutralization: suitable
• N° accesso UniProt: P20809
• Temperatura di conservazione: −20°C
• Informazioni sul gene: human ... IL11(3589)

Descrizione

Descrizione generale

Interleukin-11 (IL-11) is a pleotropic cytokine that belongs to the IL-6 family. The effects of IL-11 include hemopoiesis, macrophage differentiation and thrombopoiesis. Many cell types including osteoblasts, trophoblasts, fibroblasts, chondrocytes and a variety of tissue such as brain, gut, spinal cord and testis secrete IL-11. The cellular effects of IL-11 are mediated by a multimeric complex consisting of IL-11Rα and gp130Rβ subunits. The pathways activated by IL-11 include JAK/STAT, Ras/MAPK and Grb2 signaling. IL-11 plays a major role in inflammatory responses, immune responses by regulating the production of IgG by B cells and in tumorigenesis-related inflammation
Anti-Interleukin-11 antibody specifically reacts with human IL-11.

Specificità

The antibody neutralizes the biological activity of recombinant human IL-11.

Immunogeno

recombinant human IL-11 expressed in Sf 21 insect cells.

Applicazioni

Anti-Human IL-11 is suitable for neutralization reactions.

Stato fisico

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Nota sulla preparazione

Purified using protein G.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)