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ED4S

Acido etilendiamminotetraacetico

practical grade, ≥95%

Sinonimo/i:

EDTA, Edatamil, Tetrasodio etilendiamminotetracetato

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Informazioni su questo articolo

Formula condensata:
(NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O
Numero CAS:
Peso molecolare:
380.17 (anhydrous basis)
UNSPSC Code:
12352116
NACRES:
NA.77
PubChem Substance ID:
EC Number:
200-573-9
Beilstein/REAXYS Number:
3861753
MDL number:
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grade

practical grade

Quality Segment

assay

≥95%

form

powder

reaction suitability

reagent type: chelator

solubility

soluble, clear, colorless (32g plus 200ml of water)

InChI

1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4

InChI key

GXFFSKMBMYHTAE-UHFFFAOYSA-J

Application

Alle concentrazioni efficaci di 1-10 mM, l′EDTA è un inibitore delle metalloproteasi. L′EDTA agisce da chelante dello ione zinco nel sito attivo delle metalloproteasi e può anche inibire altre proteasi dipendenti da ioni metallo come le cisteina proteasi calcio-dipendenti. I sali disodico e tripotassico dell′EDTA sono comunemente usati come anticoagulanti. La concentrazione ottimale è di 1,5 mg per mL di sangue.
Usato per eliminare l′inibizione enzimatica da parte di tracce di metalli pesanti e per inibire gli enzimi che necessitano di cationi bivalenti come cofattori.

Preparation Note

Solubile in acqua a temperatura ambiente fino a 1,45 M. Il pH della soluzione, piuttosto viscosa, sarà compreso all′incirca tra 10 e 11.

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Questo articolo
03701E26290E5391
grade

practical grade

grade

-

grade

-

grade

-

assay

≥95%

assay

≥97.0% (KT)

assay

98%

assay

≥99.0%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

-

form

powder

solubility

soluble, clear, colorless (32g plus 200ml of water)

solubility

-

solubility

-

solubility

H2O: 0.1 M, clear, colorless

reaction suitability

reagent type: chelator

reaction suitability

-

reaction suitability

-

reaction suitability

-


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Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

target_organs

Respiratory Tract

Classe di stoccaggio

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Qi-En Yang et al.
PLoS genetics, 11(7), e1005355-e1005355 (2015-07-16)
The origin of most ovarian tumors is undefined. Here, we report development of a novel mouse model in which conditional inactivation of the tumor suppressor gene Rb1 in oocytes leads to the formation of ovarian teratomas (OTs). While parthenogenetically activated
Vladimir P Baklaushev et al.
Drug delivery, 22(3), 276-285 (2014-01-21)
Targeted drug delivery for brain tumor treatment is one of the important objectives in nanomedicine. Human glioblastoma is the most frequent and aggressive type of brain tumors. The preferential expression of membrane protein connexin 43 (Cx43) and brain-specific anion transporter



Numero articolo commerciale globale

SKUGTIN
ED4S-100G04061833609347
ED4S-500G04061833609354
ED4S-2.5KG04061833610848
ED4S-1KG04061826754436

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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