C3506

Cytosine

≥99%

• Sinonimo/i: 4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one
• Formula empirica (notazione di Hill): C₄H₅N₃O
• Numero CAS: 71-30-7
• Peso molecolare: 111.10
• Beilstein: 2637
• Numero CE: 200-749-5
• Numero MDL: MFCD00006034
• Codice UNSPSC: 41106305
• ID PubChem: 24892620
• NACRES: NA.51

Proprietà

• Origine biologica: synthetic (organic)
• Saggio: ≥99%
• Forma fisica: powder
• Punto di fusione: >300 °C (lit.)
• Solubilità: 0.5 M HCl: 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
• Stringa SMILE: NC1=NC(=O)NC=C1
• InChI: 1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8); OPTASPLRGRRNAP-UHFFFAOYSA-N

Descrizione

Applicazioni

Cytosine has been used:

• for the preparation of nucleobase solutions
• as a standard for high-performance liquid chromatography (HPLC)
• for the estimation of global methylation rate
• for nucleoside 5′-triphosphate (NTP) synthesis
• purification

Azioni biochim/fisiol

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine is a pyrimidine, which forms three hydrogen bonds to base pair with guanine. It forms a nucleotide cytidine, that is phosphorylated to cytidine 5′ monophosphate (CMP), cytidine 5′ diphosphate (CDP) and cytidine 5′ triphosphate (CTP).

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Gloves