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319R-2

Sigma-Aldrich

Cytokeratin 19 (EP72) Rabbit Monoclonal Primary Antibody

Sinonimo/i:

40-kDa keratin intermediate filament, CK-19, CK19, K19, K1CS, KRT 19, cytokeratin-19, keratin 19, type 1, keratin, type 1, 40-kd, keratin-19

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

culture supernatant

Tipo di anticorpo

primary antibodies

Clone

EP72, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (319R-24)
vial of 0.1 mL concentrate Research Use Only (319R-24-RUO)
vial of 0.5 mL concentrate (319R-25)
vial of 1.0 mL concentrate (319R-26)
vial of 1.0 mL concentrate Research Use Only (319R-26-RUO)
vial of 1.0 mL pre-dilute Research Use Only (319R-27-RUO)
vial of 1.0 mL predilute ready-to-use (319R-27)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (319R-28-RUO)
vial of 7.0 mL predilute ready-to-use (319R-28)

Produttore/marchio commerciale

Cell Marque

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200 (concentrated)

Isotipo

IgG

Controllo

bladder, colon, colon carcinoma, thyroid carcinoma

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Informazioni sul gene

human ... KRT19(3880)

Descrizione generale

Anti-cytokeratin 19 reacts with epithelia and epithelial malignancies including carcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Anti-cytokeratin 19 is very useful in differentiation of hepatocellular carcinoma from intrahepatic cholangiocarcinoma, especially in a combination of cytokeratin 7, CAM5.2, Ber-EP4/MOC31, Hep Par-1 and TTF1. Another useful application is the identification of thyroid papillary carcinoma.

Qualità

United States - IVD
Canada - IVD
European Union - IVD
Japan - RUO

Linkage

Cytokeratin 19 Positive Control Slides, Product No. 319S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Predilute: diluted in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
Concentrate: diluted in Phosphate Buffered Saline, pH 7.2, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Juan Rosai
Tumori, 89(5), 517-519 (2004-02-12)
Immunohistochemical markers of thyroid tumors can be divided into two major categories: those related to the cell types and those related to the type of pathology. The most important markers in the first category are thyroglobulin and TTF-1 for follicular
Richa Jain et al.
Applied immunohistochemistry & molecular morphology : AIMM, 18(1), 9-15 (2009-12-04)
Cytokeratin immunostaining forms the bedrock of the immunohistochemical evaluation of tumors. Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. CK19 immunohistochemistry has been used successfully in
Leandro Luongo de Matos et al.
Diagnostic pathology, 7, 97-97 (2012-08-15)
To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations. In an attempt to improve diagnostic accuracy, markers using immunocytochemistry and immunohistochemistry techniques

Articoli

Human pancreatic cancer organoid biobank (PDAC organoids) with various KRAS mutations to aide in 3D cell culture and cancer research applications.

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