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27109

Sigma-Aldrich

Acido citrico

meets analytical specification of Ph. Eur., BP, USP, E330, anhydrous, 99.5-100.5% (based on anhydrous substance)

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About This Item

Formula condensata:
HOC(COOH)(CH2COOH)2
Numero CAS:
Peso molecolare:
192.12
Beilstein:
782061
Numero CE:
Numero MDL:
Codice UNSPSC:
12352106
eCl@ss:
39021801
ID PubChem:
NACRES:
NA.21

Livello qualitativo

Saggio

99.5-100.5% (based on anhydrous substance)

Forma fisica

grit

Qualità

anhydrous
meets analytical specification of Ph. Eur., BP, USP, E330

Limite di esplosione

8 %, 65 °F

Impurezze

residual solvents, complies
≤0.0005% heavy metals (as Pb)
≤0.5% water (Karl Fischer)

Residuo alla calcinazione

≤0.05% (as SO4)

pKa 

(1) 3.13, (2) 4.76, (3) 6.4

Punto di fusione

153-159 °C (lit.)

Solubilità

water: 383 g/L at 25 °C

Anioni in tracce

chloride (Cl-): ≤50 ppm
oxalate (as oxalic acid): ≤100 ppm
sulfate (SO42-): ≤100 ppm

Cationi in tracce

As: ≤1 ppm
Ca: ≤200 ppm
Cu: ≤10 ppm
Fe: ≤10 ppm
Hg: ≤1 ppm
Pb: ≤0.5 ppm
Zn: ≤10 ppm

Compatibilità

complies for appearance of solution
complies for reaction against H2SO4

Stringa SMILE

OC(=O)CC(O)(CC(O)=O)C(O)=O

InChI

1S/C6H8O7/c7-3(8)1-6(13,5(11)12)2-4(9)10/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
KRKNYBCHXYNGOX-UHFFFAOYSA-N

Informazioni sul gene

human ... SRC(6714)

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Applicazioni

Citric acid was used as a test reagent for studying whether the novel pyridazinylpiperazine analog TPRV-1 inhibitor can reduce cough reflex induced by citric acid and capsaicin in guinea pig.

Azioni biochim/fisiol

Citric acid in dietary form can augments absorption of aluminium in antacids. It also facilitates the phytoremediation of heavy metal contaminated soil and can transform cadmium into more transportable forms.

Pittogrammi

Exclamation mark

Avvertenze

Warning

Indicazioni di pericolo

Classi di pericolo

Eye Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

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Acido citrico puriss., meets analytical specification of Ph. Eur., BP, USP, E330, 99.5-100.5% (based on anhydrous substance), grit

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P Slanina et al.
Clinical chemistry, 32(3), 539-541 (1986-03-01)
Ten healthy men ingested, twice daily between meals, during each of the seven-day experimental periods: (a) citric acid (as lemon juice), (b) Al(OH)3, or (c) Al(OH)3 + citric acid. Whole blood sampled after each dietary period was analyzed electrothermally after
Y X Chen et al.
Chemosphere, 50(6), 807-811 (2003-04-12)
Adsorption and hydroponics experiments were conducted to study the role of citric acid on the phytoremediation of heavy metal contaminated soil. The results show that addition of citric acid decreased the adsorption of both lead and cadmium, such an effect
Sum Yee Leung et al.
Cough (London, England), 3, 10-10 (2007-12-25)
Cough reflex can be induced by the pepper extract capsaicin and by low pH in guinea-pig airways. Transient receptor potential vanniloid-1 (TPRV-1) is expressed in the sensory and afferent nerve fibres in airways. We hypothesized that a novel pyridazinylpiperazine analog
Maria José Garcia-Fernandez et al.
Biofouling, 29(3), 261-271 (2013-02-27)
Prevention and management of wound infections receive a lot of attention, since the presence of micro-organisms interferes with the wound-healing process. The aim of this work was to use cyclodextrins (CDs) to endow hydrogels and gauzes with the ability to
Wayne B Batchelor et al.
Circulation, 106(12), 1470-1476 (2002-09-18)
The relative anti-aggregatory effects of currently prescribed platelet glycoprotein IIb/IIIa receptor antagonists during and after percutaneous coronary intervention for acute coronary syndromes have not been established. We randomized 70 acute coronary syndrome patients undergoing percutaneous coronary intervention to receive abciximab

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