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M8054

Sigma-Aldrich

Manganese(II) chloride tetrahydrate

meets USP testing specifications

Sinonimo/i:

Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O

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About This Item

Formula condensata:
MnCl2 · 4H2O
Numero CAS:
Peso molecolare:
197.91
Numero CE:
Numero MDL:
Codice UNSPSC:
12352302
ID PubChem:
NACRES:
NA.21

agenzia

USP/NF
meets USP testing specifications

Livello qualitativo

Saggio

98.0-101.0% dry basis

Forma fisica

flakes

Punto di fusione

58 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Stringa SMILE

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2
CNFDGXZLMLFIJV-UHFFFAOYSA-L

Categorie correlate

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

Organi bersaglio

Brain

Codice della classe di stoccaggio

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

does not flash

Punto d’infiammabilità (°C)

does not flash

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related
Geoffrey J Topping et al.
Medical physics, 40(4), 042502-042502 (2013-04-06)
Manganese(II) is employed as a contrast agent with magnetic resonance imaging (MRI) for study of neuronal activation in rats and mice. However, at the concentrations required for MRI, Mn may induce pharmacological or toxic effects. Positron emission tomography (PET) imaging
Tameshwar Ganesh et al.
Journal of magnetic resonance imaging : JMRI, 41(3), 806-813 (2014-03-05)
To investigate the potential of manganese (Mn)-enhanced MRI for sensitive detection and delineation of tumors that demonstrate little enhancement on Gd-DTPA. Eighteen nude rats bearing 1 to 2 cm in diameter orthotopic breast tumors (ZR75 and LM2) were imaged on
A G Kanthasamy et al.
Toxicology letters, 214(3), 288-295 (2012-09-22)
The role of normal cellular prion protein (PrP) remains to be fully elucidated; however, the protein is crucial for the infection and progression of prion diseases. Recent evidence indicates that PrP is a metalloprotein since the octapeptide repeat sequences in

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