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21760

Sigma-Aldrich

Carbamoylcholine chloride

purum, ≥99.0% (AT)

Sinonimo/i:

(2-Hydroxyethyl)trimethylammonium chloride carbamate, Carbachol, Carbamylcholine chloride

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About This Item

Formula condensata:
NH2COOCH2CH2N(Cl)(CH3)3
Numero CAS:
51-83-2
Peso molecolare:
182.65
Beilstein:
3917459
Numero CE:
200-127-3
Numero MDL:
MFCD00012011
Codice UNSPSC:
12352200

Grado

purum

Saggio

≥99.0% (AT)

Punto di fusione

200-210 °C (dec.)
210 °C (dec.) (lit.)

Stringa SMILE

[Cl-].C[N+](C)(C)CCOC(N)=O

InChI

1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
AIXAANGOTKPUOY-UHFFFAOYSA-N

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Altre note

Agonist of muscarinic acetylcholine receptors

Pittogrammi

Skull and crossbones
GHS06

Avvertenze

Danger

Indicazioni di pericolo

H300

Classi di pericolo

Acute Tox. 2 Oral

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
370766/1
444533/1
435621/1
407854/1
362461/1

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S Uchida et al.
European journal of pharmacology, 100(3-4), 291-298 (1984-05-04)
Multiple site models of muscarinic acetylcholine receptors (mAChR) for agonist binding were applied to curves for the inhibition of QNB binding by carbachol by using nonlinear least square regression analysis. The effects of a guanine nucleotide guanyl-5'-yl imidodiphosphate (Gpp(NH)p) and
N M Nathanson et al.
The Journal of pharmacology and experimental therapeutics, 229(2), 455-458 (1984-05-01)
Previous work has demonstrated that prolonged treatment of chick embryos in vivo with muscarinic agonists leads to a decrease in the number of muscarinic acetylcholine binding sites in the heart and a decrease in the sensitivity of isolated atria to
Kalinne Kelly Lima Gadelha et al.
Experimental physiology, 104(2), 199-208 (2018-12-19)
What is the central question of this study? Is the responsiveness of isolated segments of the rat oesophagus to contractile or relaxant stimuli susceptible to acute luminal exposure of the oesophagus to an acid solution that contains pepsin and bile
Jianmin Zhao et al.
Stem cells and development, 26(7), 528-540 (2016-12-09)
The epicardium promotes neovascularization and cardiomyocyte regeneration by generating vascular smooth muscle cells (SMCs) and producing regenerative factors after adult heart infarction. It is therefore a potential cell resource for repair of the injured heart. However, the epicardium also participates
Megan J Agajanian et al.
Cell reports, 26(1), 79-93 (2019-01-04)
β-Catenin-dependent WNT signal transduction governs development, tissue homeostasis, and a vast array of human diseases. Signal propagation through a WNT-Frizzled/LRP receptor complex requires proteins necessary for clathrin-mediated endocytosis (CME). Paradoxically, CME also negatively regulates WNT signaling through internalization and degradation

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