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AB5459

Sigma-Aldrich

Anti-GABA A Receptor α4 Antibody, CT

Chemicon®, from rabbit

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

affinity purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

rat, mouse, human

Produttore/marchio commerciale

Chemicon®

tecniche

immunoprecipitation (IP): suitable
western blot: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... GABRA4(2557)

Specificità

GABA A receptor alpha4 subunit. The apparent molecular mass of the alpha 4 subunit in rat brain membrane fractions is 64 kDa.

Immunogeno

Epitope: C-terminus
MBP fusion protein from the cytosolic loop of rat GABA A receptor alpha4 subunit.

Applicazioni

Anti-GABA A Receptor α4 Antibody, C-terminus is an antibody against GABA A Receptor α4 for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:1,000

Immunopreciptation: The antibody will immunoprecipitate 8% of all GABA A receptors in sodium dodecyl sulfate extracts of rat forebrains (150 μL) using 20 μg of antibody.

Optimal working dilutions must be determined by the end user.

Stato fisico

Affinity purified immunoglobulin in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

Stoccaggio e stabilità

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Schizophrenia and bipolar disorder are complex psychiatric disorders that affect millions of people worldwide. Evidence from gene association and postmortem studies has identified abnormalities of the gamma-aminobutyric acid (GABA) signaling system in both disorders. Abnormal GABAergic signaling and transmission could
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Journal of autism and developmental disorders, 40(6), 743-750 (2010-01-13)
We have shown altered expression of gamma-aminobutyric acid A (GABA(A)) and gamma-aminobutyric acid B (GABA(B)) receptors in the brains of subjects with autism. In the current study, we sought to verify our western blotting data for GABBR1 via qRT-PCR and

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