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AB3532P

Sigma-Aldrich

Anti-Epithelial Sodium Channel-β Antibody

Chemicon®, from rabbit

Sinonimo/i:

ENaC-beta

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

rabbit

Livello qualitativo

Forma dell’anticorpo

affinity purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

polyclonal

Purificato mediante

affinity chromatography

Reattività contro le specie

rat, mouse

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
western blot: suitable

N° accesso NCBI

N° accesso UniProt

Condizioni di spedizione

dry ice

modifica post-traduzionali bersaglio

unmodified

Informazioni sul gene

human ... SCNN1B(6338)

Specificità

Recognizes rat Epithelial Sodium Channel beta (ENaC beta). The immunogen shows no significant sequence homology with other ENaC subunits.

Immunogeno

A 20 amino acid peptide sequence near the N-terminus of rat ENaC beta. The immunogen sequence is 100% conserved in mouse, 94% in rabbit, 81% in human, 76% in ovine and 64% in xenopus.

Applicazioni

Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters

Neuroinflammation & Pain
This Anti-Epithelial Sodium Channel-β Antibody is validated for use in ELISA, WB for the detection of Epithelial Sodium Channel-β.
Western blot: 1-10 μg/mL using ECL. 83-90kDa bands, membrane preparations are recommended (Masilamani et al., 1999).

ELISA: 0.5-1.0 mg/mL using 1 mg/mL control peptide to coat plate.

Optimal working dilutions must be determined by the end user.

Stato fisico

Affinity purified immunoglobulin in PBS containing 0.1% BSA.

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Xiao Sun et al.
EMBO molecular medicine, 10(10) (2018-08-30)
The shift of cytokine profile from anti- to pro-inflammatory is the most recognizable sign of labor, although the underlying mechanism remains elusive. Here, we report that the epithelial sodium channel (ENaC) is upregulated and activated in the uterus at labor
L R E Pedersen et al.
Acta physiologica (Oxford, England), 206(2), 142-149 (2012-06-12)
We wished to determine the effect of continuous β-receptor stimulation on alveolar fluid clearance and to elucidate the mechanisms behind this effect. Alveolar fluid clearance was measured in anaesthetized rats pretreated for 72 h with the β-agonist isoproterenol (200 μg kg(-1) h(-1) sc)
Takahiro Masuda et al.
American journal of physiology. Renal physiology, 315(3), F653-F664 (2018-05-24)
The chronic intrinsic diuretic and natriuretic tone of sodium-glucose cotransporter 2 (SGLT2) inhibitors is incompletely understood because their effect on body fluid volume (BFV) has not been fully evaluated and because they often increase food and fluid intake at the

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