06-1376

Anti-SLBP Antibody

serum, from rabbit

• Sinonimo/i: Histone stem-loop-binding protein, hairpin binding protein, histone binding protein 2, histone stem-loop binding protein, stem-loop (histone) binding protein, stem-loop binding protein, HBP, Histone RNA hairpin-binding protein
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: serum
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: mouse, human
• Reattività contro le specie (prevista in base all’omologia): rat
• tecniche: immunocytochemistry: suitable; western blot: suitable
• N° accesso NCBI: NM_009193
• N° accesso UniProt: P97440
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... SLBP(7884)

Descrizione

Descrizione generale

The SLPB gene (stem-loop binding protein) encodes a protein that binds to the stem-loop structure of replication-dependent histone pre-mRNAs. Histone mRNA lack a polyadenylation signal. Consequently, the interaction of this protein with histone pre-mRNA contributes to efficient 3′ end processing by stabilizing the complex between the pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP). Expression of this protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Specificità

Antibody recognizes SLBP.

Immunogeno

KLH-conjugated linear peptide corresponding to the C-terminus of human SLBP.

Applicazioni

Immunocytochemistry:
Representative lot data.
Confocal fluorescent analysis of NIH/3T3 cells using 06-1376 (Red). Actin filaments have been labeled with AlexaFluor488 -Phalloidin (Green). Nucleus is stained with DAPI (Blue). This antibody positively stains cytoplasm and nucleus.

Research Sub Category
RNA Metabolism & Binding Proteins

Histones

Use Anti-SLBP Antibody (Rabbit Polyclonal Antibody) validated in WB, ICC to detect SLBP also known as Histone stem-loop-binding protein, HBP, Histone RNA hairpin-binding protein.

Qualità

Evaluated by Western Blotting in C2C12 cell lysates.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected SLBP in C2C12 cell lysates.

Descrizione del bersaglio

38 kDa

Stato fisico

Serum in buffer containing 0.05% sodium azide

Risultati analitici

Control
C2C12 cell lysates.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1