419508

Boron tribromide

ReagentPlus^®, ≥99%

• Sinonimo/i: Tribromoboron
• Formula empirica (notazione di Hill): BBr₃
• Numero CAS: 10294-33-4
• Peso molecolare: 250.52
• Numero CE: 233-657-9
• Numero MDL: MFCD00011312
• Codice UNSPSC: 12352101
• ID PubChem: 24866111
• NACRES: NA.22

Proprietà

• Densità del vapore: 8.6 (vs air)
• Tensione di vapore: 40 mmHg ( 14 °C)
• Nome Commerciale: ReagentPlus^®
• Saggio: ≥99%
• Colore: colorless to amber
• P. eboll.: ~90 °C (lit.)
• Punto di fusione: −46 °C (lit.)
• Densità: 2.60 g/mL at 20 °C (lit.)
• Stringa SMILE: BrB(Br)Br
• InChI: 1S/BBr3/c2-1(3)4; ILAHWRKJUDSMFH-UHFFFAOYSA-N

Descrizione

Descrizione generale

Boron tribromide is a strong Lewis acid generally employed in the deprotection of -OH and -NH groups. It is a moisture-sensitive liquid, which is also used to cleave esters or ethers into alkyl bromides.

Applicazioni

Reactant for preparation of:

• Drug intermediate 6-nitro-L-DOPA
• Luminescent polystyrene derivatives with sterically protected carbazolylborane moieties
• High-quality boron-doped graphene via Wurtz-type reductive coupling reaction
• Mercapto-(+)-methamphetamine haptens for synthesis of (+)-methamphetamine conjugate vaccines with improved epitope densities
• Micrometer-sized organic molecule-DNA hybrid structures
• Borane complexes via electrophilic aromatic borylation reactions
• A 5-HT2C receptor agonist
• Biphenyl-derivatives possessing tertiary amino groups as β-secretase(BACE1) inhibitors for the treatment of Alzheimer′s disease
• A highly near-IR region fluorescent p-extended boron aza-dipyrromethene moiety unit
• Tetrahydroisoquinoline derivatives via intramolecular cyclization of methoxy-substituted N-phenethylimides

Used to cleave aryl methyl ethers in a synthesis of a benzopyranobenzopyran from a coumarin scaffold.

Note legali

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Pittogrammi: GHS06,GHS05
• Avvertenze: Danger
• Indicazioni di pericolo: H300 + H330,H314
• Consigli di prudenza: P260 - P271 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Classi di pericolo: Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Eye Dam. 1 - Skin Corr. 1A
• Codice della classe di stoccaggio: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Dispositivi di protezione individuale: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter