Passa al contenuto
Merck

ZBTB33

zinc finger and BTB domain containing 33

Sinonimi:
ZNF-kaiso, ZNF348
Specie:
Human ZBTB33 (10009), Mouse Zbtb33 (56805), Rat Zbtb33 (501506), Domestic Rabbit ZBTB33 (100348939), domestic cat ZBTB33 (101086378), cow ZBTB33 (784871), dog ZBTB33 (100685062), Horse ZBTB33 (100062002), naked mole-rat Zbtb33 (101708806), Zebrafish zbtb33 (562507) ...Più
ID UniProtKB:
Q86T24, B2R5U6, O00319, Q7Z361, Q8IVP6, Q8N3P0
ID gene:
  • Human(10009) Summary: This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-alpha2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, May 2010]
  • Mouse(56805) zinc finger and BTB domain containing 33
  • Rat(501506) zinc finger and BTB domain containing 33
  • Domestic Rabbit(100348939) zinc finger and BTB domain containing 33
  • domestic cat(101086378) zinc finger and BTB domain containing 33
  • cow(784871) zinc finger and BTB domain containing 33
  • dog(100685062) zinc finger and BTB domain containing 33
  • Horse(100062002) zinc finger and BTB domain containing 33
  • naked mole-rat(101708806) zinc finger and BTB domain containing 33
  • Zebrafish(562507) zinc finger and BTB domain containing 33
  • chicken(422367) zinc finger and BTB domain containing 33
  • domestic guinea pig(100713178) zinc finger and BTB domain containing 33
  • sheep(101112197) zinc finger and BTB domain containing 33

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
05-659
Anti-Kaiso Antibody, clone 6F, clone 6F, Upstate®, from mouse,
Reattività con
canine, chicken, hamster, human, monkey, mouse, rat
Applicazione
electrophoretic mobility shift assay
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA005732
Anti-ZBTB33 antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
HPA000755
Anti-ZBTB33 antibody produced in rabbit, Ab1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
western blot
SAB1404770
Monoclonal Anti-ZBTB33, (C-terminal) antibody produced in mouse, clone 2B2, ascites fluid,
Reattività con
human
Applicazione
ELISA
western blot
WH0010009M1
Monoclonal Anti-ZBTB33 antibody produced in mouse, clone 2B2, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunofluorescence
western blot

esiRNA

N° Catalogo
Descrizione
Specie
EMU014281
MISSION® esiRNA, targeting mouse Zbtb33,
Specie
mouse
EHU038261
MISSION® esiRNA, targeting human ZBTB33,
Specie
human