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Merck

TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

Sinonimi:
EPI, LACI, TFI, TFPI1
Specie:
ID UniProtKB:
ID gene:
  • Human(7035) Summary: This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. [provided by RefSeq, Jul 2008]
  • Mouse(21788) tissue factor pathway inhibitor
  • Rat(29436) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • cow(508763) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • Domestic Rabbit(100009401) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • domestic guinea pig(100727170) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • dog(403921) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • sheep(101120391) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • naked mole-rat(101710461) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • domestic cat(101098813) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
  • chicken(423989) tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

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ELISA

N° Catalogo
Descrizione
Specie
Human TFPI / Tissue Factor Pathway Inhibitor ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-TFPI antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-TFPI antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
western blot
Anti-Tissue Factor Pathway Inhibitor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
Monoclonal Anti-TFPI antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human TFPI,
Specie
human
MISSION® esiRNA, targeting mouse Tfpi,
Specie
mouse