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Merck

TCEB2

transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)

Sinonimi:
ELOB, SIII
Specie:
ID UniProtKB:
ID gene:
  • Human(6923) Summary: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]
  • Mouse(67673) transcription elongation factor B (SIII), polypeptide 2
  • Rat(81807) transcription elongation factor B (SIII), polypeptide 2
  • Goat(100861051) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
  • domestic guinea pig(100713146) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
  • Zebrafish(192341) transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B)
  • cow(617277) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
  • domestic cat(100628310) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
  • dog(479873) transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Monoclonal Anti-TCEB2 antibody produced in mouse, clone 2B4, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
KD-Validated Anti TCEB2 Antibody, clone 23GB5610, Rabbit Monoclonal, clone 23GB5610, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
western blot
KD-Validated Anti TCEB2 Antibody, clone 23GB5615, Rabbit Monoclonal, clone 23GB5615, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human
Applicazione
flow cytometry
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Tceb2,
Specie
mouse
MISSION® esiRNA, targeting human TCEB2,
Specie
human