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Merck

TAPBP

TAP binding protein (tapasin)

Sinonimi:
NGS17, TAPA, TPN, TPSN
Specie:
ID UniProtKB:
ID gene:
  • Human(6892) Summary: This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(21356) TAP binding protein
  • Rat(25217) TAP binding protein (tapasin)
  • dog(481740) TAP binding protein (tapasin)
  • naked mole-rat(101719224) TAP binding protein (tapasin)
  • chicken(417048) TAP binding protein (tapasin)
  • Zebrafish(30163) TAP binding protein
  • domestic cat(101091023) TAP binding protein (tapasin)
  • sheep(100170652) TAP binding protein (tapasin)
  • domestic guinea pig(100735947) TAP binding protein (tapasin)
  • Horse(100061515) TAP binding protein (tapasin)
  • cow(504335) TAP binding protein (tapasin)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Tapasin Antibody, clone 7F6, clone 7F6, from rat,
Reattività con
human
Applicazione
flow cytometry
Anti-TAPBP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Tapasin, from rabbit,
Reattività con
mouse
Applicazione
immunoprecipitation (IP)
western blot
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-TAPBP antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, horse, human, mouse, pig, rat, sheep
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human TAPBP (2),
Specie
human
MISSION® esiRNA, targeting human TAPBP (1),
Specie
human