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Merck

SRF

serum response factor (c-fos serum response element-binding transcription factor)

Sinonimi:
MCM1
Specie:
ID UniProtKB:
ID gene:
  • Human(6722) Summary: This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). [provided by RefSeq, Jul 2008]
  • Mouse(20807) serum response factor
  • Rat(501099) serum response factor (c-fos serum response element-binding transcription factor)
  • fruit fly(252723) Surf wings
  • chicken(396103) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic cat(101085210) serum response factor (c-fos serum response element-binding transcription factor)
  • dog(612861) serum response factor (c-fos serum response element-binding transcription factor)
  • cow(533039) serum response factor (c-fos serum response element-binding transcription factor)
  • sheep(101111402) serum response factor (c-fos serum response element-binding transcription factor)
  • domestic guinea pig(100715998) serum response factor (c-fos serum response element-binding transcription factor)
  • naked mole-rat(101719000) serum response factor (c-fos serum response element-binding transcription factor)

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-SRF Antibody, clone 1H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-SRF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-SRF antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
bovine, canine, human, mouse
Applicazione
ELISA
western blot
Anti-SRF Antibody, clone 2C5, ,
Reattività con
human, mouse
Applicazione
immunohistochemistry
Anti-SRF antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry

western blot

Proteins

N° Catalogo
Descrizione
Specie
C-fos, proto oncogene human, recombinant, expressed in insect cells, ≥70% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human SRF,
Specie
human