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Merck

SAFB

scaffold attachment factor B

Sinonimi:
HAP, HET, SAF-B1, SAFB1
Specie:
Human SAFB (6294), Mouse Safb (224903), Rat Safb (64196), chicken SAFB (426047), Zebrafish safb (321979), domestic guinea pig Safb (100718986), naked mole-rat Safb (101713322), domestic cat SAFB (101092244), cow SAFB (539785), dog SAFB (485028)
ID UniProtKB:
Q15424, A0AV56, B7Z5B6, B7ZLP6, F5H0H3, O60406, Q59HH8
ID gene:
  • Human(6294) Summary: This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
  • Mouse(224903) scaffold attachment factor B
  • Rat(64196) scaffold attachment factor B
  • chicken(426047) scaffold attachment factor B
  • Zebrafish(321979) scaffold attachment factor B
  • domestic guinea pig(100718986) scaffold attachment factor B
  • naked mole-rat(101713322) scaffold attachment factor B
  • domestic cat(101092244) scaffold attachment factor B
  • cow(539785) scaffold attachment factor B
  • dog(485028) scaffold attachment factor B

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB2702149
Monoclonal Anti-SAFB antibody produced in mouse, ,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
HPA020076
Anti-SAFB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
05-588
Anti-HET/SAF-B Antibody, clone 6F7, clone 6F7, Upstate®, from mouse,
Reattività con
human
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA016832
Anti-SAFB antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
ZRB2171
Anti-SAFB Antibody, clone 2N15-L2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunohistochemistry
western blot

esiRNA

N° Catalogo
Descrizione
Specie
EMU167381
MISSION® esiRNA, targeting mouse Safb,
Specie
mouse
EHU009431
MISSION® esiRNA, targeting human SAFB,
Specie
human