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Merck

S1PR5

sphingosine-1-phosphate receptor 5

Sinonimi:
EDG8, Edg-8, S1P5, SPPR-1, SPPR-2
Specie:
ID UniProtKB:
ID gene:
  • Human(53637) Summary: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
  • Mouse(94226) sphingosine-1-phosphate receptor 5
  • Rat(60399) sphingosine-1-phosphate receptor 5
  • domestic cat(101091512) sphingosine-1-phosphate receptor 5
  • dog(610828) sphingosine-1-phosphate receptor 5
  • cow(517533) sphingosine-1-phosphate receptor 5
  • sheep(101117761) sphingosine-1-phosphate receptor 5

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numero di prodotto
Descrizione
Specie
SEW2871, ≥98% (HPLC), solid,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo anti-recettore per la sfingosina 1-fosfato 5 (S1P5), clone 13F9.1, clone 13F9.1, from mouse,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
Anti-EDG8 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
ELISA
immunofluorescence

immunohistochemistry

Small Molecule - Mixed Agonist/Antagonist

Numero di prodotto
Descrizione
Specie
Sphingosine 1-phosphate, ≥95%, powder,
Specie
human
D-erythro-Dihydrosphingosine 1-phosphate, ≥98% (TLC), waxy solid,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human S1PR5,
Specie
human
MISSION® esiRNA, targeting mouse S1pr5,
Specie
mouse