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Merck

PRDM16

PR domain containing 16

Sinonimi:
CMD1LL, LVNC8, MEL1, PFM13
Specie:
Human PRDM16 (63976), Mouse Prdm16 (70673), Rat Prdm16 (100366024), dog PRDM16 (479582), domestic cat PRDM16 (101090880), sheep PRDM16 (101120004), cow PRDM16 (100137803), Horse PRDM16 (100060844), Zebrafish prdm16 (559174), domestic guinea pig Prdm16 (100714489) ...Più
ID UniProtKB:
Q9HAZ2, A6NHQ8, B1AJP7, B1AJP8, B1AJP9, B1WB48, Q8WYJ9, Q9C0I8
ID gene:
  • Human(63976) Summary: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(70673) PR domain containing 16
  • Rat(100366024) PR domain containing 16
  • dog(479582) PR domain containing 16
  • domestic cat(101090880) PR domain containing 16
  • sheep(101120004) PR domain containing 16
  • cow(100137803) PR domain containing 16
  • Horse(100060844) PR domain containing 16
  • Zebrafish(559174) PR domain containing 16
  • domestic guinea pig(100714489) PR domain containing 16
  • naked mole-rat(101721685) PR domain containing 16
  • chicken(419388) PR domain containing 16

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
ABD130
Anti-PRDM16 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human, rat
Applicazione
immunofluorescence
immunohistochemistry
western blot
ABE543
Anti-PRDM16 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
bovine, canine, guinea pig, horse, human, nonhuman primates
Applicazione
immunohistochemistry
immunoprecipitation (IP)
western blot
HPA060467
Anti-PRDM16 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
SAB3500989
Anti-PRDM16 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse
Applicazione
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB1300006
Anti-PRDM16 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
immunohistochemistry