Passa al contenuto
Merck

PDK1

pyruvate dehydrogenase kinase, isozyme 1

Sinonimi:
Specie:
ID UniProtKB:
ID gene:
  • Human(5163) Summary: Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2013]
  • Mouse(228026) pyruvate dehydrogenase kinase, isoenzyme 1
  • Rat(116551) pyruvate dehydrogenase kinase, isozyme 1
  • fruit fly(38017) Phosphoinositide-dependent kinase 1
  • Zebrafish(555840) pyruvate dehydrogenase kinase, isozyme 1
  • Thale Cress(830330) 3'-phosphoinositide-dependent protein kinase 1
  • Horse(100064091) pyruvate dehydrogenase kinase, isozyme 1
  • domestic guinea pig(100715937) pyruvate dehydrogenase kinase, isozyme 1
  • naked mole-rat(101705587) pyruvate dehydrogenase kinase, isozyme 1
  • sheep(101113205) pyruvate dehydrogenase kinase, isozyme 1
  • Domestic Rabbit(100351323) pyruvate dehydrogenase kinase, isozyme 1
  • cow(528655) pyruvate dehydrogenase kinase, isozyme 1
  • domestic cat(101092705) pyruvate dehydrogenase kinase, isozyme 1
  • dog(476828) pyruvate dehydrogenase kinase, isozyme 1
  • chicken(425972) pyruvate dehydrogenase kinase, isozyme 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Activator

N° Catalogo
Descrizione
Specie
Dichloroacetic acid, ReagentPlus®, ≥99%,
Specie
human, rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-PDH kinase 1 Antibody, clone 1C7-H1 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-PDK1 antibody produced in mouse, clone 3E1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
Anti-PDK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-PDK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human, mouse, rat
Applicazione
ELISA
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Dichloroacetic acid, ReagentPlus®, ≥99%,
Specie
human, rat
Sodium dichloroacetate, 98%,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
PDHK1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Pdk1,
Specie
mouse
MISSION® esiRNA, targeting human PDK1,
Specie
human