PARK2
parkinson protein 2, E3 ubiquitin protein ligase (parkin)
Sinonimi:
AR-JP, LPRS2, PDJ, PRKN
Specie:
Human PARK2 (5071), Mouse Park2 (50873), Rat Park2 (56816), cow PARK2 (530858), naked mole-rat Park2 (101700770), domestic guinea pig Park2 (100724550), Horse PARK2 (100057832), Zebrafish park2 (550328), chicken PARK2 (421577), dog PARK2 (612316) ...Più
ID UniProtKB:
ID gene:
- Human(5071) Summary: The precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq, Jul 2008]
- Mouse(50873) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- Rat(56816) parkinson protein 2, E3 ubiquitin protein ligase
- cow(530858) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- naked mole-rat(101700770) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic guinea pig(100724550) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Horse(100057832) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- Zebrafish(550328) Parkinson disease (autosomal recessive, juvenile) 2, parkin
- chicken(421577) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- dog(612316) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- domestic cat(101098228) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
- sheep(101113503) parkinson protein 2, E3 ubiquitin protein ligase (parkin)
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Parkin Antibody, clone PRK8, ascites fluid, clone PRK8, Upstate®,
Reattività con
human, mouse
Applicazione
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-PARK2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
canine, human, mouse, rat
Applicazione
ELISA
western blot
western blot
ANTI-PARKIN(C-TERMINAL) antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
flow cytometry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Parkin antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anticorpo anti-Parkin, aa 305-323, serum, Chemicon®,
Reattività con
human, rat
Applicazione
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
esiRNA
N° Catalogo
Descrizione
Specie