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Merck

NQO1

NAD(P)H dehydrogenase, quinone 1

Sinonimi:
DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Specie:
ID UniProtKB:
ID gene:
  • Human(1728) Summary: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(18104) NAD(P)H dehydrogenase, quinone 1
  • Rat(24314) NAD(P)H dehydrogenase, quinone 1
  • chicken(769737) NAD(P)H dehydrogenase, quinone 1
  • domestic guinea pig(100135582) NAD(P)H dehydrogenase, quinone 1
  • domestic cat(101097859) NAD(P)H dehydrogenase, quinone 1
  • Zebrafish(322506) NAD(P)H dehydrogenase, quinone 1
  • cow(519632) NAD(P)H dehydrogenase, quinone 1
  • sheep(101121876) NAD(P)H dehydrogenase, quinone 1
  • naked mole-rat(101711262) NAD(P)H dehydrogenase, quinone 1
  • dog(610935) NAD(P)H dehydrogenase, quinone 1

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ELISA

N° Catalogo
Descrizione
Specie
Human NQO-1 ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-NQO1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-NQO1 Antibody, clone 1D12 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-NQO1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, mouse
Applicazione
western blot
Anti-NQO1 antibody produced in rabbit, ,
Reattività con
human, mouse
Applicazione
immunofluorescence
western blot
Anti-NQO1 Rabbit pAb, liquid, Calbiochem®,
Reattività con
human, mouse
Applicazione

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Menadione, crystalline,
Specie
human
Menadione, meets USP testing specifications,
Specie
human
Menadione (K3), analytical standard,
Specie
human

Proteins

N° Catalogo
Descrizione
Specie
DT Diaphorase (NQO1) human, lyophilized powder, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Specie
human
NQO1 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Nqo1,
Specie
mouse
MISSION® esiRNA, targeting human NQO1,
Specie
human