NPHS2
nephrosis 2, idiopathic, steroid-resistant (podocin)
Sinonimi:
PDCN, SRN1
Specie:
Human NPHS2 (7827), Mouse Nphs2 (170484), Rat Nphs2 (170672), Zebrafish nphs2 (557914), chicken NPHS2 (424422), dog NPHS2 (490323), sheep NPHS2 (101121618), cow NPHS2 (537633), domestic guinea pig Nphs2 (100716190), naked mole-rat Nphs2 (101704471)
ID UniProtKB:
ID gene:
- Human(7827) Summary: This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
- Mouse(170484) nephrosis 2, podocin
- Rat(170672) nephrosis 2, idiopathic, steroid-resistant
- Zebrafish(557914) nephrosis 2, idiopathic, steroid-resistant (podocin)
- chicken(424422) nephrosis 2, idiopathic, steroid-resistant (podocin)
- dog(490323) nephrosis 2, idiopathic, steroid-resistant (podocin)
- sheep(101121618) nephrosis 2, idiopathic, steroid-resistant (podocin)
- cow(537633) nephrosis 2, idiopathic, steroid-resistant (podocin)
- domestic guinea pig(100716190) nephrosis 2, idiopathic, steroid-resistant (podocin)
- naked mole-rat(101704471) nephrosis 2, idiopathic, steroid-resistant (podocin)
- domestic cat(101084927) nephrosis 2, idiopathic, steroid-resistant (podocin)
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Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Podocin, Mouse monoclonal, clone PD-65, purified from hybridoma cell culture,
Reattività con
bovine, human, mouse, rat
Applicazione
immunofluorescence
western blot
western blot
Anti-NPHS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-NPHS2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
Anti-Podocin antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reattività con
human, mouse, rat
Applicazione
immunofluorescence
western blot
western blot
esiRNA
N° Catalogo
Descrizione
Specie