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Merck

MARCH4

membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase

Sinonimi:
MARCH-IV, RNF174
Specie:
ID UniProtKB:
ID gene:
  • Human(57574) Summary: MARCH4 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]
  • Mouse(381270) membrane-associated ring finger (C3HC4) 4
  • Rat(367295) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • sheep(101107500) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • Zebrafish(562065) membrane-associated ring finger (C3HC4) 4
  • Horse(100050538) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • cow(527624) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • dog(488515) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • naked mole-rat(101718651) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • domestic guinea pig(100725253) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
  • domestic cat(101082766) membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-MARCH4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human MARCH4,
Specie
human