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Merck

LDB3

LIM domain binding 3

Sinonimi:
CMD1C, CYPHER, LDB3Z1, LDB3Z4, LVNC3, MFM4, ORACLE, PDLIM6, ZASP
Specie:
ID UniProtKB:
ID gene:
  • Human(11155) Summary: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains. [provided by RefSeq, Jan 2010]
  • Mouse(24131) LIM domain binding 3
  • Rat(498587) LIM domain binding 3
  • chicken(423610) LIM domain binding 3
  • Domestic Rabbit(100348927) LIM domain binding 3
  • cow(536781) LIM domain binding 3
  • dog(479269) LIM domain binding 3
  • domestic guinea pig(100724737) LIM domain binding 3
  • sheep(101111515) LIM domain binding 3

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Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-LDB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human LDB3,
Specie
human