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Merck

IL12A

interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

Sinonimi:
CLMF, IL-12A, NFSK, NKSF1, P35
Specie:
ID UniProtKB:
ID gene:
  • Human(3592) Summary: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
  • Mouse(16159) interleukin 12a
  • Rat(84405) interleukin 12A
  • domestic guinea pig(100379543) interleukin 12a
  • chicken(407090) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Zebrafish(445410) interleukin 12a
  • Horse(100034215) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • domestic cat(493741) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • dog(403977) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • cow(281856) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • Goat(100861293) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • sheep(443064) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
  • naked mole-rat(101701392) interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)

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ELISA

N° Catalogo
Descrizione
Specie
Human IL-12 p70 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Specie
human
Mouse IL-12 P40/70 ELISA Kit, for serum, plasma and cell culture supernatant,
Specie
mouse
Rhesus Macaque IL12A / IL12B ELISA Kit, ,
Specie
Porcine IL12A / IL12B ELISA Kit, ,
Specie

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-IL-12A Antibody, clone 1G10 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
baboon, bovine, canine, feline, goat, human, monkey, mouse, porcine, sheep
Applicazione
affinity binding assay
flow cytometry

western blot
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum,
Reattività con
mouse
Applicazione
neutralization
western blot
Anti-Interleukin-12 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Reattività con
human
Applicazione
neutralization
Anti-IL-12 alpha Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Proteins

N° Catalogo
Descrizione
Specie
IL-12 human, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
human
IL-12 from mouse, recombinant, expressed in CHO cells, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Specie
mouse
IL-35 (mouse): FC (human), recombinant, expressed in CHO cells,
Specie
mouse
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Specie
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Specie
mouse

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Il12a,
Specie
mouse
MISSION® esiRNA, targeting human IL12A,
Specie
human