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Merck

HRAS

Harvey rat sarcoma viral oncogene homolog

Sinonimi:
C-BAS/HAS, C-H-RAS, C-HA-RAS1, CTLO, H-RASIDX, HAMSV, HRAS1, K-RAS, N-RAS, RASH1
Specie:
ID UniProtKB:
ID gene:
  • Human(3265) Summary: This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Rat(293621) Harvey rat sarcoma virus oncogene
  • dog(403735) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • cow(100298939) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • naked mole-rat(101716053) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • chicken(396229) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • domestic guinea pig(100735038) v-Ha-ras Harvey rat sarcoma viral oncogene homolog
  • sheep(101104357) v-Ha-ras Harvey rat sarcoma viral oncogene homolog

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Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Guanosina 5′-trifosfato, ≥95% (HPLC), powder,
Specie
human
Inosine 5′-triphosphate trisodium salt, ≥95%,
Specie
human
Guanosine 5′-triphosphate sodium salt solution, HPLC purified, aqueous solution for RNA polymerase transcription,
Specie
human
2′,3′-Dideoxyguanosine 5′-triphosphate sodium salt, ≥90% (HPLC),
Specie
human
Erastin, ≥98% (HPLC),
Specie
mouse, rat, human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Monoclonal Anti-HRAS antibody produced in mouse, clone H-RAS-03,
Reattività con
human
Applicazione
western blot
Anti-c-H-Ras (Ab-1) Mouse mAb (F235-1.7.1), liquid, clone F235-1.7.1, Calbiochem®,
Reattività con
human, mouse, rat
Applicazione
Anti-H-Ras Antibody, clone 3B13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
ELISA
affinity binding assay

western blot
Anti-Ha-Ras Antibody, clone MC57, rabbit monoclonal, culture supernatant, clone MC57, from rabbit,
Reattività con
human, mouse, rat
Applicazione
western blot
Anti-HRAS antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human HRAS,
Specie
human