Passa al contenuto
Merck

GCLM

glutamate-cysteine ligase, modifier subunit

Sinonimi:
GLCLR
Specie:
ID UniProtKB:
ID gene:
  • Human(2730) Summary: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008]
  • Mouse(14630) glutamate-cysteine ligase, modifier subunit
  • Rat(29739) glutamate cysteine ligase, modifier subunit
  • dog(612283) glutamate-cysteine ligase, modifier subunit
  • domestic guinea pig(100725164) glutamate-cysteine ligase, modifier subunit
  • domestic cat(101081562) glutamate-cysteine ligase, modifier subunit
  • fruit fly(248194) Glutamate-cysteine ligase modifier subunit
  • chicken(424492) glutamate-cysteine ligase, modifier subunit
  • naked mole-rat(101703324) glutamate-cysteine ligase, modifier subunit
  • sheep(101117899) glutamate-cysteine ligase, modifier subunit
  • Zebrafish(333974) glutamate-cysteine ligase, modifier subunit
  • cow(525659) glutamate-cysteine ligase, modifier subunit

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GCLM Antibody, clone 1D19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, monkey, mouse
Applicazione
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, ,
Reattività con
Applicazione
western blot
Anti-GCLM antibody produced in rabbit, ,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
Anti-GCLM antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
L-Buthionine-sulfoximine, ≥97% (TLC),
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human GCLM,
Specie
human
MISSION® esiRNA, targeting mouse Gclm,
Specie
mouse