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Merck

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

Sinonimi:
EIG10, EJM7, GEFSP5
Specie:
ID UniProtKB:
ID gene:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Meprobamate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
Midazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Diazepam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Oxazepam solution, 1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Alprazolam solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Etomidate, >98% (HPLC), powder,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
Specie
human
Ganaxolone, ≥98% (HPLC), solid,
Specie
human, mouse
2,6-Diisopropylphenol, 97%,
Specie
human
Flumazenil, >99% (HPLC), solid,
Specie
rat, human
5α-Pregnan-3α-ol-20-one, solid,
Specie
human, mouse, rat

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
Reattività con
bovine, dog, human, mouse, rabbit
Applicazione
immunohistochemistry
western blot

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human GABRD,
Specie
human
MISSION® esiRNA, targeting mouse Gabrd,
Specie
mouse