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Merck

FBXW8

F-box and WD repeat domain containing 8

Sinonimi:
FBW6, FBW8, FBX29, FBXO29, FBXW6
Specie:
ID UniProtKB:
ID gene:
  • Human(26259) Summary: This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(231672) F-box and WD-40 domain protein 8
  • Rat(304522) F-box and WD repeat domain containing 8
  • sheep(101108081) F-box and WD repeat domain containing 8
  • domestic guinea pig(100728842) F-box and WD repeat domain containing 8
  • naked mole-rat(101714467) F-box and WD repeat domain containing 8
  • Zebrafish(100136859) F-box and WD repeat domain containing 8
  • chicken(417024) F-box and WD repeat domain containing 8
  • dog(486288) F-box and WD repeat domain containing 8
  • domestic cat(101091406) F-box and WD repeat domain containing 8
  • cow(787118) F-box and WD repeat domain containing 8

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-FBXW8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-FBXW8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting mouse Fbxw8,
Specie
mouse
MISSION® esiRNA, targeting human FBXW8,
Specie
human