Passa al contenuto
Merck

CRYGD

crystallin, gamma D

Sinonimi:
CACA, CCA3, CCP, CRYG4, CTRCT4, PCC, cry-g-D
Specie:
Human CRYGD (1421), Mouse Crygd (12967), Rat Crygd (24278), dog CRYGD (488495), domestic cat CRYGD (101092875), cow CRYGD (281723), sheep CRYGD (101106832)
ID UniProtKB:
P07320, Q17RF7, Q53R51, Q99681
ID gene:
  • Human(1421) Summary: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
  • Mouse(12967) crystallin, gamma D
  • Rat(24278) crystallin, gamma D
  • dog(488495) crystallin, gamma D
  • domestic cat(101092875) crystallin, gamma D
  • cow(281723) crystallin, gamma D
  • sheep(101106832) crystallin, gamma D

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
SAB1105749
Anti-CRYGD (151-165) antibody produced in rabbit, IgG fraction of antiserum,
Reattività con
human
Applicazione
western blot
HPA041269
Anti-CRYGD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
SAB1405662
Anti-CRYGD antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot
WH0001421M3
Monoclonal Anti-CRYGD antibody produced in mouse, clone 4E12, purified immunoglobulin, buffered aqueous solution,
Reattività con
mouse
Applicazione
ELISA
western blot
SAB1410244
Anti-CRYGD antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
western blot

esiRNA

N° Catalogo
Descrizione
Specie
EMU163311
MISSION® esiRNA, targeting mouse Crygd,
Specie
mouse