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Merck

CASP5

caspase 5, apoptosis-related cysteine peptidase

Sinonimi:
ICE(rel)III, ICEREL-III, ICH-3
Specie:
Human CASP5 (838)
ID UniProtKB:
P51878, B4DKP5, Q0QVY7, Q0QVY8, Q0QVZ0, Q0QVZ1, Q0QVZ2, Q14DD6
ID gene:
  • Human(838) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010]

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Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
SAB6012022
Anti Caspase 5 Antibody, clone 23GB3315, Rabbit Monoclonal, clone 23GB3315, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reattività con
human, rat
Applicazione
flow cytometry
immunofluorescence
western blot
HPA040937
Anti-CASP5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
ABS445
Anti-Caspase-5 Antibody, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
immunocytochemistry
immunofluorescence
western blot

Proteins

Numero di prodotto
Descrizione
Specie
C6482
Caspase 5 human, recombinant, expressed in E. coli, 5,000 units/mg protein,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
EHU127011
MISSION® esiRNA, targeting human CASP5,
Specie
human