BCCIP
BRCA2 and CDKN1A interacting protein
Sinonimi:
TOK-1, TOK1
Specie:
Human BCCIP (56647), Mouse Bccip (66165), Rat Bccip (361666), dog BCCIP (477864), Zebrafish bccip (541348), chicken BCCIP (426225), naked mole-rat Bccip (101721059), domestic cat BCCIP (101100756), cow BCCIP (512466), sheep BCCIP (101116189)
ID UniProtKB:
ID gene:
- Human(56647) Summary: This gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
- Mouse(66165) BRCA2 and CDKN1A interacting protein
- Rat(361666) BRCA2 and CDKN1A interacting protein
- dog(477864) BRCA2 and CDKN1A interacting protein
- Zebrafish(541348) BRCA2 and CDKN1A interacting protein
- chicken(426225) BRCA2 and CDKN1A interacting protein
- naked mole-rat(101721059) BRCA2 and CDKN1A interacting protein
- domestic cat(101100756) BRCA2 and CDKN1A interacting protein
- cow(512466) BRCA2 and CDKN1A interacting protein
- sheep(101116189) BRCA2 and CDKN1A interacting protein
- domestic guinea pig(100733090) BRCA2 and CDKN1A interacting protein
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-BCCIP antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Anti-BCCIP antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Anti-BCCIP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-BCCIP (C-term) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot