AR
androgen receptor
Sinonimi:
AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM
Specie:
Human AR (367), Mouse Ar (11835), Rat Ar (24208), fruit fly ar (44503), Zebrafish ar (100005148), chicken AR (422165), dog AR (403588), domestic cat AR (101081787), domestic cat AR (751827), Horse AR (100033980) ...Più
ID UniProtKB:
ID gene:
- Human(367) Summary: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- Mouse(11835) androgen receptor
- Rat(24208) androgen receptor
- fruit fly(44503) abdomen rotatum
- Zebrafish(100005148) androgen receptor
- chicken(422165) androgen receptor
- dog(403588) androgen receptor
- domestic cat(101081787) androgen receptor
- domestic cat(751827) androgen receptor
- Horse(100033980) androgen receptor
- cow(280675) androgen receptor
- sheep(443042) androgen receptor
- Goat(100860827) androgen receptor
- Domestic Rabbit(100009193) androgen receptor
- domestic guinea pig(100726891) androgen receptor
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Small Molecule - Activator
N° Catalogo
Descrizione
Specie
Small Molecule - Agonist
N° Catalogo
Descrizione
Specie
Testosterone solution, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Methandienone solution, 1.0 mg/mL in 1,2-dimethoxyethane, ampule of 1 mL, certified reference material, Cerilliant®,
Specie
human
Small Molecule - Antagonist
N° Catalogo
Descrizione
Specie
Antibodies
N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-Androgen Receptor (C-term) antibody, Rabbit monoclonal, clone SP242, recombinant, expressed in proprietary host, affinity isolated antibody,
Reattività con
dog, human, mouse, pig, rabbit, rat
Applicazione
immunohistochemistry
Anti-phospho-Androgen Receptor (Ser81) Antibody, rabbit monoclonal, culture supernatant, Upstate®,
Reattività con
human
Applicazione
western blot
Anti-Androgen Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reattività con
human
Applicazione
ChIP
ELISA
immunohistochemistry
western blot
ELISA
immunohistochemistry
western blot
Anti-Androgen Receptor antibody, Rabbit monoclonal, clone SP107, recombinant, expressed in proprietary host, affinity isolated antibody,
Reattività con
dog, human, mouse, pig, rat
Applicazione
immunohistochemistry
Anti-AR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Small Molecule - Blocker
N° Catalogo
Descrizione
Specie
Small Molecule - Inhibitor
Small Molecule - Ligand
N° Catalogo
Descrizione
Specie