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Merck

ANPEP

alanyl (membrane) aminopeptidase

Sinonimi:
APN, CD13, GP150, LAP1, P150, PEPN
Specie:
ID UniProtKB:
ID gene:
  • Human(290) Summary: Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq, Jul 2008]
  • Mouse(16790) alanyl (membrane) aminopeptidase
  • Rat(81641) alanyl (membrane) aminopeptidase
  • naked mole-rat(101706035) alanyl (membrane) aminopeptidase
  • domestic guinea pig(100727522) alanyl (membrane) aminopeptidase
  • sheep(101104860) alanyl (membrane) aminopeptidase
  • chicken(395667) alanyl (membrane) aminopeptidase
  • Domestic Rabbit(100009167) alanyl (membrane) aminopeptidase
  • cow(404191) alanyl (membrane) aminopeptidase
  • domestic cat(493785) alanyl (membrane) aminopeptidase
  • dog(403913) alanyl (membrane) aminopeptidase
  • Horse(100050397) alanyl (membrane) aminopeptidase

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ELISA

N° Catalogo
Descrizione
Specie
Human Aminopeptidase N ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-ANPEP antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry

western blot
Milli-Mark® Anti-CD13-FITC Antibody, clone WM-47, clone WM-47, Milli-Mark®, from mouse,
Reattività con
human
Applicazione
flow cytometry
Anti-CD13 antibody, Rabbit monoclonal, clone SP182, recombinant, expressed in proprietary host, affinity isolated antibody,
Reattività con
human, pig, rabbit
Applicazione
flow cytometry
immunohistochemistry
Anti-APN/CD13 Antibody, clone 1D20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, rat
Applicazione
affinity binding assay
flow cytometry

immunohistochemistry

western blot
Monoclonal Anti-CD13 antibody produced in mouse, clone WM15, purified immunoglobulin, buffered aqueous solution,
Reattività con
human, nonhuman primates
Applicazione
flow cytometry
immunohistochemistry

immunoprecipitation (IP)

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
Actinonin, ,
Specie
human
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutyryl]-L-leucine, 97%,
Specie
human, mouse, rat
Flavone, ≥99.0%,
Specie
human, rat, mouse

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting human ANPEP,
Specie
human
MISSION® esiRNA, targeting mouse Anpep,
Specie
mouse