ANAPC5
anaphase promoting complex subunit 5
Sinonimi:
APC5
Specie:
Human ANAPC5 (51433), Mouse Anapc5 (59008), Rat Anapc5 (288671), sheep ANAPC5 (101102840), Domestic Rabbit ANAPC5 (100350286), domestic guinea pig Anapc5 (100726899), naked mole-rat Anapc5 (101724399), Zebrafish anapc5 (322854), chicken ANAPC5 (416842), dog ANAPC5 (477471) ...Più
ID UniProtKB:
ID gene:
- Human(51433) Summary: This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a. [provided by RefSeq, Nov 2008]
- Mouse(59008) anaphase-promoting complex subunit 5
- Rat(288671) anaphase-promoting complex subunit 5
- sheep(101102840) anaphase promoting complex subunit 5
- Domestic Rabbit(100350286) anaphase promoting complex subunit 5
- domestic guinea pig(100726899) anaphase promoting complex subunit 5
- naked mole-rat(101724399) anaphase promoting complex subunit 5
- Zebrafish(322854) anaphase promoting complex subunit 5
- chicken(416842) anaphase promoting complex subunit 5
- dog(477471) anaphase promoting complex subunit 5
- Horse(100058548) anaphase promoting complex subunit 5
- cow(540537) anaphase promoting complex subunit 5
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Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-ANAPC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-ANAPC5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
western blot