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Merck

ABCA1

ATP-binding cassette, sub-family A (ABC1), member 1

Sinonimi:
ABC-1, ABC1, CERP, HDLDT1, TGD
Specie:
Human ABCA1 (19), Mouse Abca1 (11303), Rat Abca1 (313210), chicken ABCA1 (373945), cow ABCA1 (535379), sheep ABCA1 (101119015), domestic cat ABCA1 (101083885), Horse ABCA1 (100054241), dog ABCA1 (481651), Thale Cress ABCA1 (818768) ...Più
ID UniProtKB:
O95477, Q5VX33, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08
ID gene:
  • Human(19) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
  • Mouse(11303) ATP-binding cassette, sub-family A (ABC1), member 1
  • Rat(313210) ATP-binding cassette, subfamily A (ABC1), member 1
  • chicken(373945) ATP-binding cassette, sub-family A (ABC1), member 1
  • cow(535379) ATP-binding cassette, sub-family A (ABC1), member 1
  • sheep(101119015) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic cat(101083885) ATP-binding cassette, sub-family A (ABC1), member 1
  • Horse(100054241) ATP-binding cassette, sub-family A (ABC1), member 1
  • dog(481651) ATP-binding cassette, sub-family A (ABC1), member 1
  • Thale Cress(818768) ABC transporter A family member 1
  • naked mole-rat(101704546) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic guinea pig(100720792) ATP-binding cassette, sub-family A (ABC1), member 1
  • Domestic Rabbit(100356765) ATP-binding cassette, sub-family A (ABC1), member 1

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
T2320
T0901317, ≥98%,
Specie
human

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
MAB10005
Anti-ABCA1 Antibody, clone AB.H10, clone AB.H10, Chemicon®, from mouse,
Reattività con
chicken, human, mouse
Applicazione
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB2106639
Anti-ABCA1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
western blot
SAB4300712
Anti-ABCA1 antibody produced in rabbit, affinity isolated antibody,
Reattività con
human, mouse, rat
Applicazione
western blot
MABN893
Anti-ABCA1 Antibody, clone MABI98-7, clone MAB198-7, from rat,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
HPA057283
Anti-ABCA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
1563309
Probucol, United States Pharmacopeia (USP) Reference Standard,
Specie
human
P9672
Probucol, analytical standard,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
EMU068891
MISSION® esiRNA, targeting mouse Abca1,
Specie
mouse