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Landscape of the regulatory elements for lysine 2-hydroxyisobutyrylation pathway.

Cell research (2017-12-02)
He Huang, Zhouqing Luo, Shankang Qi, Jing Huang, Peng Xu, Xiuxuan Wang, Li Gao, Fangyi Li, Jian Wang, Wenhui Zhao, Wei Gu, Zhucheng Chen, Lunzhi Dai, Junbiao Dai, Yingming Zhao
RÉSUMÉ

Short-chain fatty acids and their corresponding acyl-CoAs sit at the crossroads of metabolic pathways and play important roles in diverse cellular processes. They are also precursors for protein post-translational lysine acylation modifications. A noteworthy example is the newly identified lysine 2-hydroxyisobutyrylation (K

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