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Curvature-induced expulsion of actomyosin bundles during cytokinetic ring contraction.

eLife (2016-10-25)
Junqi Huang, Ting Gang Chew, Ying Gu, Saravanan Palani, Anton Kamnev, Douglas S Martin, Nicholas J Carter, Robert Anthony Cross, Snezhana Oliferenko, Mohan K Balasubramanian
RÉSUMÉ

Many eukaryotes assemble a ring-shaped actomyosin network that contracts to drive cytokinesis. Unlike actomyosin in sarcomeres, which cycles through contraction and relaxation, the cytokinetic ring disassembles during contraction through an unknown mechanism. Here we find in

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Monoclonal Anti-GFP IgG (H+L), CF 633 antibody produced in mouse, ~1 mg/mL, clone 9F9.F9, purified immunoglobulin